INDIANAPOLIS -- RJ Barrett scored 33 points and Zion Williamson added 28 in their first college games, leading No. 4 Duke over No. 2 Kentucky 118-84 on Tuesday night in the season-opening Champions Classic.
It was the most lopsided defeat in coach John Calipari's tenure at Kentucky and marked the eighth time in 10 meetings the Blue Devils have beaten the Wildcats.
Both Barrett and Williamson surpassed Marvin Bagley III's program record for points by a freshman in his debut at 25. Cam Reddish added 22 points and Tre Jones had six, giving Duke's freshmen a combined 89 points.
The teams set a Classic record for most combined points, set hours earlier in No. 1 Kansas' 92-87 victory over No. 10 Michigan State.
Keldon Johnson scored 23 points to lead Kentucky. Graduate transfer Reid Travis added 22 for the Wildcats, who had won all nine previous season openers under Calipari.
The highly-anticipated game between two of the nation's most successful college programs was never close. Duke led by 10 after six minutes and extended the lead to 34-13 less than 10 minutes into the game.
The Blue Devils didn't stop with that flurry.
After making it 59-42 at halftime, Duke kept pulling away throughout the second half. Barrett's dunk with 16:11 remaining made it 72-47, Alex O'Connell's 3-pointer with 11:45 remaining made it 91-54 and Duke topped the 100-point mark on another dunk by Barrett with 7:36 left.
Kentucky only got as close as 27 until the waning moments.
Barrett was 13 of 26 from the field while Williamson was 11 of 13 with seven rebounds.